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AICAR The Hyped Wonder Pill To Lose Body Weight
In the recent past there has been a lot of debate amongst the scientific community to develop a formula or a pill that could on one hand fulfill all the nutritional requirements, and on the other hand reduce excess body weight.
Another important aspect expected from these magic pills is improvement in physical and athletic performance. An answer to a few of these questions appears to have been unveiled by a group of researchers working at the Salk Institute. They have recently published their very interesting findings on this wonder drug AICAR.
What is AICAR?
AICAR is an abbreviated form for aminoimidazole carboxamide ribonucleotide which is naturally synthesized in the body as well. It is biochemical intermediate in the physiological generation of inosine monophosphate. This improves the activity of the Adenosine Monophosphate activated protein kinase, this is directly responsible for an increased glucose uptake by the muscles resulting in faster burning of calories and eventually better muscular performance. The important effect of AICAR that the researchers purportedly claimed in their research published in a very reputed scientific journal the Cell is that, AICAR leads to change in the functionality of the muscle fibre, which is converted from the low efficiency high energy consuming type to the more endurance bearing, low energy consuming effective fibre type.
Evidence for AICAR in body weight loss
Although, the authors report that the administration of AICAR improved the performance of mice by 40-45% and their calorie consumption was much faster as well, still there is no evidence provided in their study regarding the effect of consumption of this drug on improving the body weight loss or fat reduction. It could although be a possibility that faster energy consumption may certainly enhance the ability to shred extra pounds. The authors also suspected some toxic effects of this drug, and recommend further trials before the drug could be approved for human use as performance enhancer.
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